Ultrasound-Guided Core Biopsy with or without Vacuum Assistance

An Ultrasound Guided Core Biopsy is a tissue sampling performed under the guidance of ultrasound.

What’s Involved

The biopsy is performed while you are lying on your back with your arm raised above your head. The skin is cleansed with an antiseptic solution and sterile towels are placed around the breast. The breast is numbed with a local anesthetic at the biopsy site.

A small nick is made in the skin and the biopsy needle is inserted through the skin nick to the area in the breast under the guidance of ultrasound. The needle is placed in the breast three to five times to obtain adequate tissue samples of the site.

After an adequate sampling of tissue is done, the radiologist may place a small metallic clip at the biopsy site in the breast. This clip will mark where the biopsy occurred if surgery would be needed in this area. You will not be able to feel the clip nor would it interfere with metal detectors or having an MRI done in the future.

Standard digital mammogram views will be done to reestablish a baseline after biopsy and verify clip placement. Steri strips and a pressure dressing is applied. The nurse will go over written discharge instructions with you.

Preparing for Your Biopsy

  • Please eat before your procedure.
  • Call your insurance company to pre-certify and inform them you are having this outpatient procedure to verify coverage.
  • Although you will not be given any medications to make you drowsy, you may choose to have someone drive you to and from the Breast Care Center.
  • Do not take any medications containing aspirin, ibuprofen or Aleve three days prior to your biopsy. The nurse will talk to you about allergies and any other blood thinners you may be on. You may take acetaminophen.


The pathologist’s report takes at least three working days. Your physician will inform you of the results when they become available. If the biopsy is benign, the radiologist may recommend a four to six month follow-up to reevaluate the biopsy area.